The Blue Jays were beaten by the Tampa Bay Devil Rays 6-2.
The big blow came in the sixth inning when Tampa's Carl Crawford hit a two-run home run.
The Jays have the day off today and will begin a weekend series against the Texas Rangers on Friday.
The Argonauts will battle the Montreal Alouettes this evening.
Damon Allen has been named the starting quarterback, with Mike McMahon coming off the bench if needed.
Kickoff - 7pm in Montreal.
The Maple Leafs shutout the Oshawa Dodgers last night 2-0.
Toronto wins the best-of-seven playoff series four games to one.
The Leafs will now move on the Intercounty semi-finals, where they will face the Brantford Red Sox.
The Vaughan Italia Shooters beat GS United 2-0, in the opening round of the Open Canada Cup tournament.
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